Dr. Kathleen Gough
My primary research focus is spectrochemical imaging of heterogeneous samples, from biological tissues (Alzheimer disease brain, stressed tendons) to diatoms and composite polymers. We use both FTIR microscopy, with Focal Plane Array, and Raman Microscopy. Image at left shows a senile plaque in AD brain, ~20 microns diameter, imaged with FTIR, at 1 micron pixel resolution.
Website: Gough Group
Dr. Sabine Kuss
In our laboratory, we are investigating important questions at the interface of chemistry, biology and medical research, employing a combination of analytical chemistry, physical chemical and electrochemical techniques as well as experimental methods in molecular biology and biochemistry. Disease detection, quantification of cell membrane receptor activity and position, monitoring the correlation of membrane pumps with feature activity, and electrochemical sensing of receptor-drug interactions are focus of research in our group. We are currently working on projects in the fields of endocrinological diseases, antibiotic drug resistance in pathogens, mitochondrial dysfunctions and cancer development.
Website: Sabine Kuss Group
Dr. Hélène Perreault
Our laboratory uses mass spectrometry, especially matrix-assisted laser desorption/ionization (MALDI), to study the composition and structure of proteins, glycoproteins and oligosaccharides. Glycans found in antibodies are a main focus area and for these we develop sample preparation techniques using pull down, chromatography and electrophoresis to make samples amenable to mass spectrometry. We also use electrospray ionization (ESI-MS).
Website: Perreault Group
Dr. Gregg Tomy
Research in the Tomy group focuses on developing analytical methods to measure chemicals used in commerce that have the potential to be persistent, bioaccumulative and toxic. We use high resolution mass spectrometry to unearth previously unreported chemicals in the environment.